Publications — The Hogan Laboratory

Idelman G, Rizza CF, Marella S, Sharma A, Chakraborty S, Tay HL, Tomar S, Ganesan V, Schuler CF 4th, Baker JR, Hogan SP.

Mucosal Immunol. 2024 Oct;17(5):1029-1044. doi: 10.1016/j.mucimm.2024.07.003. Epub 2024 Jul 20.

PMID: 39038754

IL-4-STAT6 axis amplifies histamine-induced vascular endothelial dysfunction and hypovolemic shock.

Krempski J, Yamani A, Thota LNR, Marella S, Ganesan V, Sharma A, Kaneshige A, Bai L, Zhou H, Foster PS, Wang S, Obi AT, Hogan SP.

J Allergy Clin Immunol. 2024 May 20:S0091-6749(24)00520-7. doi: 10.1016/j.jaci.2024.05.009.

PMID: 38777155

2023

IL-13-induced STAT3-dependent signaling networks regulate esophageal epithelial proliferation in eosinophilic esophagitis.

Marella S, Sharma A, Ganesan V, Ferrer-Torres D, Krempski J, Idelman G, Clark S, Nasiri Z, Vanoni S, Zeng C, Dlugosz AA, Zhou H, Wang S, Doyle AD,

Wright BL, Spence J, Chehade M, Hogan SP.

J Allergy Clin Immunol. 2023 Aug 29:S0091-6749(23)01100-4. doi: 10.1016/j.jaci.2023.07.021.

PMID: 37652141

Mucosal IgA immune complex induces immunomodulatory responses in allergic airway and intestinal Th2 disease.

Elesela S, Arzola-Martínez L, Rasky A, Ptaschinski C, Hogan SP, Lukacs NW.

J Allergy Clin Immunol. 2023 Aug 19:S0091-6749(23)01058-8. doi: 10.1016/j.jaci.2023.08.006.

PMID: 37604310

Transepidermal water loss rises before food anaphylaxis and predicts food challenge outcomes.

Schuler CF 4th, O'Shea KM, Troost JP, Kaul B, Launius CM, Cannon J, Manthei DM, Freigeh GE, Sanders GM, Hogan SP, Lukacs NW, Baker JR Jr.

J Clin Invest. 2023 Aug 15;133(16):e168965. doi: 10.1172/JCI168965.

PMID: 37402149

C5aR1 activation in mice controls inflammatory eosinophil recruitment and functions in allergic asthma.

Wiese AV, Duhn J, Korkmaz RÜ, Quell KM, Osman I, Ender F, Schröder T, Lewkowich I, Hogan S, Huber-Lang M, Gumprecht F, König P, Köhl J, Laumonnier Y.

Allergy. 2023 Jul;78(7):1893-1908. doi: 10.1111/all.15670. Epub 2023 Feb 21.

PMID: 36757006

Acute systemic myeloid inflammatory and stress response in severe food allergic reactions.

Sharma A, Rijavec M, Tomar S, Yamani A, Ganesan V, Krempski J, Schuler CF 4th, Bunyavanich S, Korosec P, Hogan SP.

Clin Exp Allergy. 2023 May;53(5):536-549. doi: 10.1111/cea.14273. Epub 2023 Feb 9.

PMID: 36756745

IL-4 receptor alpha signaling alters oral food challenge and immunotherapy outcomes in mice.

Ganesan V, Sharma A, Tomar S, Schuler CF 4th, Hogan SP.

J Allergy Clin Immunol. 2023 Jan;151(1):182-191.e6. doi: 10.1016/j.jaci.2022.07.011. Epub 2022 Aug 4.

PMID: 35934083

2022

Integrative transcriptomic analysis in human and mouse model of anaphylaxis identifies gene signatures associated with cell movement, migration and neuroinflammatory signalling.

Rijavec M, Maver A, Turner PJ, Hočevar K, Košnik M, Yamani A, Hogan SP, Custovic A, Peterlin B, Korošec P.

Front Immunol. 2022 Dec 8;13:1016165. doi: 10.3389/fimmu.2022.1016165. eCollection 2022.

PMID: 36569939

Intestinal epithelial BLT1 promotes mucosal repair.

Hayashi S, Muraleedharan CK, Oku M, Tomar S, Hogan SP, Quiros M, Parkos CA, Nusrat A.

JCI Insight. 2022 Dec 8;7(23):e162392. doi: 10.1172/jci.insight.162392.

PMID: 36301666

Mapping the adult human esophagus in vivo and in vitro.

Ferrer-Torres D, Wu JH, Zhang CJ, Hammer MA, Dame MK, Wu A, Holloway EM, Karpoff K, McCarthy CL, Bohm MS, Cuttitta AJ, Tigani DJ, Huang S, Tsai YH, Miller AJ, Walker T, Bayer DE,

Hogan SP, Turgeon DK, Lin J, Higgins PDR, Sexton J, Spence JR.

Development. 2022 Oct 15;149(20):dev200614. doi: 10.1242/dev.200614. Epub 2022 Oct 24.

PMID: 36278875

Eosinophilic esophagitis: Immune mechanisms and therapeutic targets.

Khokhar D, Marella S, Idelman G, Chang JW, Chehade M, Hogan SP.

Clin Exp Allergy. 2022 Oct;52(10):1142-1156. doi: 10.1111/cea.14196. Epub 2022 Jul 19.

PMID: 35778876

2021

Intestinal goblet cells sample and deliver lumenal antigens by regulated endocytic uptake and transcytosis.

Gustafsson JK, Davis JE, Rappai T, McDonald KG, Kulkarni DH, Knoop KA, Hogan SP, Fitzpatrick JA, Lencer WI, Newberry RD.

Elife. 2021 Oct 22;10:e67292. doi: 10.7554/eLife.67292.

PMID: 34677124

Severity grading system for acute allergic reactions: A multidisciplinary Delphi study.

Hogan SP.

J Allergy Clin Immunol. 2021 Jul;148(1):86-88. doi: 10.1016/j.jaci.2021.04.031. Epub 2021 May 6.

PMID: 33965430

Uridine diphosphate-glucose/P2Y14R axis is a nonchemokine pathway that selectively promotes eosinophil accumulation.

Foster PS, Tay HL, Hogan SP.

J Clin Invest. 2021 Apr 1;131(7):e147735. doi: 10.1172/JCI147735.

PMID: 33792564

2020

Synchronization of mothers and offspring promotes tolerance and limits allergy.

Knoop KA, McDonald KG, Coughlin PE, Kulkarni DH, Gustafsson JK, Rusconi B, John V, Ndao IM, Beigelman A, Good M, Warner BB, Elson CO, Hsieh CS, Hogan SP, Tarr PI, Newberry RD.

JCI Insight. 2020 Aug 6;5(15):e137943. doi: 10.1172/jci.insight.137943.

PMID: 32759496

Recent advances in mechanisms of food allergy and anaphylaxis.

Tomar S, Hogan SP.

F1000Res. 2020 Jul 31;9:F1000 Faculty Rev-863. doi: 10.12688/f1000research.25638.1. eCollection 2020.

PMID: 32789004

Goblet cell associated antigen passages support the induction and maintenance of oral tolerance.

Kulkarni DH, Gustafsson JK, Knoop KA, McDonald KG, Bidani SS, Davis JE, Floyd AN, Hogan SP, Hsieh CS, Newberry RD.

Mucosal Immunol. 2020 Mar;13(2):271-282. doi: 10.1038/s41385-019-0240-7. Epub 2019 Dec 9.

PMID: 31819172

2019

Identification of anoctamin 1 (ANO1) as a key driver of esophageal epithelial proliferation in eosinophilic esophagitis.

Vanoni S, Zeng C, Marella S, Uddin J, Wu D, Arora K, Ptaschinski C, Que J, Noah T, Waggoner L, Barski A, Kartashov A, Rochman M, Wen T, Martin L, Spence J, Collins M, Mukkada V, Putnam P, Naren A, Chehade M, Rothenberg ME, Hogan SP.

J Allergy Clin Immunol. 2020 Jan;145(1):239-254.e2. doi: 10.1016/j.jaci.2019.07.049. Epub 2019 Oct 21.

PMID: 31647967

Developments in the mechanisms of allergy in 2018 through the eyes of Clinical and Experimental Allergy, Part I.

Roberts G, Almqvist C, Boyle R, Crane J, Hogan SP, Marsland B, Saglani S, Woodfolk JA.

Clin Exp Allergy. 2019 Dec;49(12):1541-1549. doi: 10.1111/cea.13532.

PMID: 31833127

IL-13-induced intestinal secretory epithelial cell antigen passages are required for IgE-mediated food-induced anaphylaxis.

Noah TK, Knoop KA, McDonald KG, Gustafsson JK, Waggoner L, Vanoni S, Batie M, Arora K, Naren AP, Wang YH, Lukacs NW, Munitz A, Helmrath MA, Mahe MM, Newberry RD, Hogan SP.

J Allergy Clin Immunol. 2019 Oct;144(4):1058-1073.e3. doi: 10.1016/j.jaci.2019.04.030. Epub 2019 Jun 5.

PMID: 31175877

Deletion of ΔdblGata motif leads to increased predisposition and severity of IgE-mediated food-induced anaphylaxis response.

Sharma S, Tomar S, Dharne M, Ganesan V, Smith A, Yang Y, Waggoner L, Wang YH, Hogan SP.

PLoS One. 2019 Aug 1;14(8):e0219375. doi: 10.1371/journal.pone.0219375. eCollection 2019.

PMID: 31369572

17β-Estradiol protects the esophageal epithelium from IL-13-induced barrier dysfunction and remodeling.

Wheeler JC, Vanoni S, Zeng C, Waggoner L, Yang Y, Wu D, Uddin J, Karns R, Kottyan L, Mukkada V, Rothenberg ME, Hogan SP.

J Allergy Clin Immunol. 2019 Jun;143(6):2131-2146. doi: 10.1016/j.jaci.2018.10.070. Epub 2018 Dec 20.

PMID: 30578870

What's old is new again: Batf transcription factors and Th9 cells.

Sundrud MS, Hogan SP.

Mucosal Immunol. 2019 May;12(3):583-585. doi: 10.1038/s41385-019-0155-3. Epub 2019 Mar 4.

PMID: 30833634

C5a receptor 1-/- mice are protected from the development of IgE-mediated experimental food allergy.

Kordowski A, Reinicke AT, Wu D, Orinska Z, Hagemann P, Huber-Lang M, Lee JB, Wang YH, Hogan SP, Köhl J.

Allergy. 2019 Apr;74(4):767-779. doi: 10.1111/all.13637. Epub 2018 Nov 12.

PMID: 30341777

Alarming eosinophils to combat tumors.

Munitz A, Hogan SP.

Nat Immunol. 2019 Mar;20(3):250-252. doi: 10.1038/s41590-019-0318-0.

PMID: 30778244

Halogen bonding in mono- and dihydrated halobenzene.

Hogan SWL, van Mourik T.

J Comput Chem. 2019 Jan 30;40(3):554-561. doi: 10.1002/jcc.25733. Epub 2018 Dec 14.

PMID: 30549084

2018

Loss of GTPase of immunity-associated protein 5 (Gimap5) promotes pathogenic CD4+ T-cell development and allergic airway disease.

Patterson AR, Bolcas P, Lampe K, Cantrell R, Ruff B, Lewkowich I, Hogan SP, Janssen EM, Bleesing J, Khurana Hershey GK, Hoebe K.

J Allergy Clin Immunol. 2019 Jan;143(1):245-257.e6. doi: 10.1016/j.jaci.2018.10.018. Epub 2018 Oct 25.

PMID: 30616774

Solute carrier family 9, subfamily A, member 3 (SLC9A3)/sodium-hydrogen exchanger member 3 (NHE3) dysregulation and dilated intercellular spaces in patients with eosinophilic esophagitis.

Zeng C, Vanoni S, Wu D, Caldwell JM, Wheeler JC, Arora K, Noah TK, Waggoner L, Besse JA, Yamani AN, Uddin J, Rochman M, Wen T, Chehade M, Collins MH, Mukkada VA, Putnam PE, Naren AP, Rothenberg ME, Hogan SP.

J Allergy Clin Immunol. 2018 Dec;142(6):1843-1855. doi: 10.1016/j.jaci.2018.03.017. Epub 2018 May 4.

PMID: 29729938

The vascular endothelial specific IL-4 receptor alpha-ABL1 kinase signaling axis regulates the severity of IgE-mediated anaphylactic reactions.

Yamani A, Wu D, Waggoner L, Noah T, Koleske AJ, Finkelman F, Hogan SP.

J Allergy Clin Immunol. 2018 Oct;142(4):1159-1172.e5. doi: 10.1016/j.jaci.2017.08.046. Epub 2017 Nov 17.

PMID: 29157947

Investigating innate immune mechanisms in early-life development and outcomes of food allergy.

Dang A, Logsdon S, Hogan SP.

J Allergy Clin Immunol. 2018 Sep;142(3):790-792. doi: 10.1016/j.jaci.2018.08.001. Epub 2018 Aug 7.

PMID: 30096392

Mechanically induced development and maturation of human intestinal organoids in vivo.

Poling HM, Wu D, Brown N, Baker M, Hausfeld TA, Huynh N, Chaffron S, Dunn JCY, Hogan SP, Wells JM, Helmrath MA, Mahe MM.

Nat Biomed Eng. 2018 Jun;2(6):429-442. doi: 10.1038/s41551-018-0243-9. Epub 2018 Jun 4.

PMID: 30151330

Enhanced survival following oral and systemic Salmonella enterica serovar Typhimurium infection in polymeric immunoglobulin receptor knockout mice.

Betz KJ, Maier EA, Amarachintha S, Wu D, Karmele EP, Kinder JM, Steinbrecher KA, McNeal MM, Luzader DH, Hogan SP, Moore SR.

PLoS One. 2018 Jun 1;13(6):e0198434. doi: 10.1371/journal.pone.0198434. eCollection 2018.

PMID: 29856838

Peroxisomal β-oxidation regulates whole body metabolism, inflammatory vigor, and pathogenesis of nonalcoholic fatty liver disease.

Moreno-Fernandez ME, Giles DA, Stankiewicz TE, Sheridan R, Karns R, Cappelletti M, Lampe K, Mukherjee R, Sina C, Sallese A, Bridges JP, Hogan SP, Aronow BJ, Hoebe K, Divanovic S.

JCI Insight. 2018 Mar 22;3(6):e93626. doi: 10.1172/jci.insight.93626.

PMID: 29563328

2017

Microbial antigen encounter during a preweaning interval is critical for tolerance to gut bacteria.

Knoop KA, Gustafsson JK, McDonald KG, Kulkarni DH, Coughlin PE, McCrate S, Kim D, Hsieh CS, Hogan SP, Elson CO, Tarr PI, Newberry RD.

Sci Immunol. 2017 Dec 15;2(18):eaao1314. doi: 10.1126/sciimmunol.aao1314.

PMID: 29246946

Erratum: Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling.

Giles DA, Moreno-Fernandez ME, Stankiewicz TE, Graspeuntner S, Cappelletti M, Wu D, Mukherjee R, Chan CC, Lawson MJ, Klarquist J, Sünderhauf A, Softic S, Kahn CR, Stemmer K, Iwakura Y, Aronow BJ, Karns R, Steinbrecher KA, Karp CL, Sheridan R, Shanmukhappa SK, Reynaud D, Haslam DB, Sina C, Rupp J, Hogan SP, Divanovic S.

Nat Med. 2017 Oct 6;23(10):1241. doi: 10.1038/nm1017-1241c.

PMID: 28985207

Modeling TH 2 responses and airway inflammation to understand fundamental mechanisms regulating the pathogenesis of asthma.

Foster PS, Maltby S, Rosenberg HF, Tay HL, Hogan SP, Collison AM, Yang M, Kaiko GE, Hansbro PM, Kumar RK, Mattes J.

Immunol Rev. 2017 Jul;278(1):20-40. doi: 10.1111/imr.12549.

PMID: 28658543

Thermoneutral housing exacerbates nonalcoholic fatty liver disease in mice and allows for sex-independent disease modeling.

Nat Med. 2017 Jul;23(7):829-838. doi: 10.1038/nm.4346. Epub 2017 Jun 12.

PMID: 28604704

Manipulating DNA damage-response signaling for the treatment of immune-mediated diseases.

McNally JP, Millen SH, Chaturvedi V, Lakes N, Terrell CE, Elfers EE, Carroll KR, Hogan SP, Andreassen PR, Kanter J, Allen CE, Henry MM, Greenberg JN, Ladisch S, Hermiston ML, Joyce M, Hildeman DA, Katz JD, Jordan MB.

Proc Natl Acad Sci U S A. 2017 Jun 13;114(24):E4782-E4791. doi: 10.1073/pnas.1703683114. Epub 2017 May 22.

PMID: 28533414

Corrigendum: Competition between Hydrogen and Halogen Bonding in Halogenated 1-Methyluracil:Water Systems.

Hogan SW, van Mourik T.

J Comput Chem. 2017 May 5;38(12):933. doi: 10.1002/jcc.24759. Epub 2017 Feb 28.

PMID: 28245057

Mucosal Expression of Type 2 and Type 17 Immune Response Genes Distinguishes Ulcerative Colitis From Colon-Only Crohn's Disease in Treatment-Naive Pediatric Patients.

Rosen MJ, Karns R, Vallance JE, Bezold R, Waddell A, Collins MH, Haberman Y, Minar P, Baldassano RN, Hyams JS, Baker SS, Kellermayer R, Noe JD, Griffiths AM, Rosh JR, Crandall WV, Heyman MB, Mack DR, Kappelman MD, Markowitz J, Moulton DE, Leleiko NS, Walters TD, Kugathasan S, Wilson KT, Hogan SP, Denson LA.

Gastroenterology. 2017 May;152(6):1345-1357.e7. doi: 10.1053/j.gastro.2017.01.016. Epub 2017 Jan 26.

PMID: 28132889

The Phosphatidylcholine Transfer Protein Stard7 is Required for Mitochondrial and Epithelial Cell Homeostasis.

Yang L, Na CL, Luo S, Wu D, Hogan S, Huang T, Weaver TE.

Sci Rep. 2017 Apr 12;7:46416. doi: 10.1038/srep46416.

PMID: 28401922

Type I interferons regulate susceptibility to inflammation-induced preterm birth.

Cappelletti M, Presicce P, Lawson MJ, Chaturvedi V, Stankiewicz TE, Vanoni S, Harley IT, McAlees JW, Giles DA, Moreno-Fernandez ME, Rueda CM, Senthamaraikannan P, Sun X, Karns R, Hoebe K, Janssen EM, Karp CL, Hildeman DA, Hogan SP, Kallapur SG, Chougnet CA, Way SS, Divanovic S.

JCI Insight. 2017 Mar 9;2(5):e91288. doi: 10.1172/jci.insight.91288.

PMID: 28289719

Myeloid-derived NF-κB negative regulation of PU.1 and c/EBP-β-driven pro-inflammatory cytokine production restrains LPS-induced shock.

Vanoni S, Tsai YT, Waddell A, Waggoner L, Klarquist J, Divanovic S, Hoebe K, Steinbrecher KA, Hogan SP.

Innate Immun. 2017 Feb;23(2):175-187. doi: 10.1177/1753425916681444. Epub 2016 Dec 8.

PMID: 27932520

2016

Myeloid-derived NF-κB negative regulation of PU.1 and c/EBP-β-driven pro-inflammatory cytokine production restrains LPS-induced shock.

Vanoni S, Tsai YT, Waddell A, Waggoner L, Klarquist J, Divanovic S, Hoebe K, Steinbrecher KA, Hogan SP.

Innate Immun. 2017 Feb;23(2):175-187. doi: 10.1177/1753425916681444. Epub 2016 Dec 8.

PMID: 27932520

Role of matrix metalloproteinase-8 as a mediator of injury in intestinal ischemia and reperfusion.

Daly MC, Atkinson SJ, Varisco BM, Klingbeil L, Hake P, Lahni P, Piraino G, Wu D, Hogan SP, Zingarelli B, Wong HR.

FASEB J. 2016 Oct;30(10):3453-3460. doi: 10.1096/fj.201600242R. Epub 2016 Jul 19.

PMID: 27435263

Self-Assembled Monolayers of Oligophenylenecarboxylic Acids on Silver Formed at the Liquid-Solid Interface.

Aitchison H, Lu H, Hogan SW, Früchtl H, Cebula I, Zharnikov M, Buck M.

Langmuir. 2016 Sep 20;32(37):9397-409. doi: 10.1021/acs.langmuir.6b01773. Epub 2016 Sep 2.

PMID: 27588836

Cyclophilin D regulates necrosis, but not apoptosis, of murine eosinophils.

Zhu X, Hogan SP, Molkentin JD, Zimmermann N.

Am J Physiol Gastrointest Liver Physiol. 2016 Apr 15;310(8):G609-17. doi: 10.1152/ajpgi.00389.2015. Epub 2016 Feb 18.

PMID: 26893161

IL-25 and CD4(+) TH2 cells enhance type 2 innate lymphoid cell-derived IL-13 production, which promotes IgE-mediated experimental food allergy.

Lee JB, Chen CY, Liu B, Mugge L, Angkasekwinai P, Facchinetti V, Dong C, Liu YJ, Rothenberg ME, Hogan SP, Finkelman FD, Wang YH.

J Allergy Clin Immunol. 2016 Apr;137(4):1216-1225.e5. doi: 10.1016/j.jaci.2015.09.019. Epub 2015 Nov 10.

PMID: 26560039

Competition between hydrogen and halogen bonding in halogenated 1-methyluracil: Water systems.

Hogan SW, van Mourik T.

J Comput Chem. 2016 Mar 30;37(8):763-70. doi: 10.1002/jcc.24264. Epub 2016 Jan 15.

PMID: 26773851

2015

Loss of IL-4Rα-mediated PI3K signaling accelerates the progression of IgE/mast cell-mediated reactions.

Sledd J, Wu D, Ahrens R, Lee J, Waggoner L, Tsai YT, Wang YH, Hogan SP.

Immun Inflamm Dis. 2015 Sep 17;3(4):420-30. doi: 10.1002/iid3.80. eCollection 2015 Dec.

PMID: 26734464

IL-33 Signaling Protects from Murine Oxazolone Colitis by Supporting Intestinal Epithelial Function.

Waddell A, Vallance JE, Moore PD, Hummel AT, Wu D, Shanmukhappa SK, Fei L, Washington MK, Minar P, Coburn LA, Nakae S, Wilson KT, Denson LA, Hogan SP, Rosen MJ.

Inflamm Bowel Dis. 2015 Dec;21(12):2737-46. doi: 10.1097/MIB.0000000000000532.

PMID: 26313694

Induction of Interleukin-9-Producing Mucosal Mast Cells Promotes Susceptibility to IgE-Mediated Experimental Food Allergy.

Chen CY, Lee JB, Liu B, Ohta S, Wang PY, Kartashov AV, Mugge L, Abonia JP, Barski A, Izuhara K, Rothenberg ME, Finkelman FD, Hogan SP, Wang YH.

Immunity. 2015 Oct 20;43(4):788-802. doi: 10.1016/j.immuni.2015.08.020. Epub 2015 Sep 22.

PMID: 26410628

Factor XIII Transglutaminase Supports the Resolution of Mucosal Damage in Experimental Colitis.

Andersson C, Kvist PH, McElhinney K, Baylis R, Gram LK, Pelzer H, Lauritzen B, Holm TL, Hogan S, Wu D, Turpin B, Miller W, Palumbo JS.

PLoS One. 2015 Jun 22;10(6):e0128113. doi: 10.1371/journal.pone.0128113. eCollection 2015.

PMID: 26098308

2014

Differential eosinophil and mast cell regulation: mast cell viability and accumulation in inflammatory tissue are independent of proton-sensing receptor GPR65.

Zhu X, Mose E, Hogan SP, Zimmermann N.

Am J Physiol Gastrointest Liver Physiol. 2014 Jun 1;306(11):G974-82. doi: 10.1152/ajpgi.00341.2013. Epub 2014 Apr 17.

PMID: 24742990

The non-anticoagulation costs of atrial fibrillation management: findings from an observational study in NHS Primary Care.

Kassianos G, Arden C, Hogan S, Baldock L, Fuat A.

Drugs Context. 2014 Apr 9;3:212254. doi: 10.7573/dic.212254. eCollection 2014.

PMID: 24744805

New class of metal bound molecular switches involving H-tautomerism.

Simpson GJ, Hogan SW, Caffio M, Adams CJ, Früchtl H, van Mourik T, Schaub R.

Nano Lett. 2014 Feb 12;14(2):634-9. doi: 10.1021/nl4038517. Epub 2014 Jan 31.

PMID: 24471795

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